Takeda Pharmaceutical Company Limited

A proven people‑focused commercial strategist with extensive global experience to lead Takeda Canada's next chapter of growth and impact.

TORONTO, March 2, 2026  /CNW/ - Takeda Canada Inc. ("Takeda") is pleased to announce the appointment of Alan Walshe as General Manager for Canada.

Alan brings 17 years of experience with Takeda and its predecessor companies, most recently serving as Global Head of Commercial Strategy for the Plasma‑Derived Therapies Business Unit.

"Alan's depth of commercial expertise and global perspective, combined with his people‑focused leadership style and long‑standing commitment to Takeda's mission, make him an outstanding choice to lead our Canadian business and further strengthen our presence in this critical market," said Jean-Luc Delay, President of the Europe and Canada Business Unit at Takeda. "I am confident that under Alan's leadership, we will further advance access to innovative medicines and deliver transformative impact for patients across Canada."

As a leading values-based, R&D-driven biopharmaceutical company headquartered in Japan, Takeda is focused on bringing better health and a brighter future to people around the world. Operating in Canada since 2009, we aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines.

"I am honoured to step into the role of General Manager for Takeda in Canada and to join such a dedicated and talented team, said Alan Walshe. "I am deeply confident in our ability to accelerate Takeda's impact here. Canada is one of Takeda's most important and dynamic markets, and I look forward to building on our strong foundation as we expand access to innovative therapies, strengthen partnerships, and advance meaningful outcomes for patients and communities nationwide."

Alan holds Master Degrees in Biotechnology (Immunology & Genetics) from University College Dublin (UCD), and in Management from UCD Michael Smurfit Graduate Business School.

About Takeda Canada Inc.

Takeda Canada Inc. is the Canadian organization of Takeda Pharmaceutical Company Limited (TSE: 4502/NYSE: TAK).  Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&D-driven biopharmaceutical company headquartered in Japan, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit: https://www.takeda.com/en-ca/

SOURCE Takeda Canada Inc.

TORONTO, Dec. 16, 2025 /CNW/ - Takeda Canada Inc. ("Takeda") is pleased to announce that FRUZAQLA^TM (fruquintinib capsules) will now be reimbursed by BC Cancer as a treatment option for adult patients with metastatic colorectal cancer (mCRC) who have been previously treated with, or are not considered candidates, for available standard therapies.[1]  This treatment is available to patients under certain criteria.

"Colorectal cancer remains the second leading cause of cancer-related deaths in Canada. For patients with advanced disease, timely access to new and innovative therapies is important," said Barry D. Stein, President and CEO of Colorectal Cancer Canada. "As both an advocate and someone who has lived experience with stage IV colon cancer, I am encouraged to see this new treatment become available. It offers renewed hope for potentially improved outcomes and quality of life for those facing the most challenging stages of this disease."

mCRC refers to cancer of the colon that has spread to other parts of the body (called distant metastasis), such as to the liver or lungs.[2] It's estimated that over 3,600 people in British Columbia are diagnosed with colorectal cancer (CRC) every year, with rising rates in young people under age 50.[3] Approximately 70 per cent of patients with CRC will experience metastatic disease, whether at diagnosis or after treatment with metastases being the main cause of CRC-related death.[4]^,[5]

FRUZAQLA^TM was reimbursed in Quebec by Régie de l'assurance maladie (RAMQ), and under the federal Non-Insured Health Benefits (NIHB) Formulary, both under certain criteria patients need to meet. It received market authorization by Health Canada in September 2024 and received a positive reimbursement recommendation by Canada's Drug Agency (CDA-AMC) and Institut national d'excellence en santé et services sociaux (INESSS).  

"The impact of mCRC can be profound, affecting survival and quality of life for thousands of people in this province. The reimbursement of FRUZAQLA^TM is another step forward in Takeda's efforts to advancing care for all Canadians living with metastatic colorectal cancer," said Kiran Dharani, Oncology Country Head, Takeda Canada. "We remain committed to working collaboratively with provincial partners and advocates to ensure that all patients can achieve better health and a brighter future."  

About FRUZAQLA^TM
FRUZAQLA^TM (fruquintinib capsules) is a selective oral inhibitor of vascular endothelial growth factors receptors (VEGFR) -1, -2, and -3 with half maximal inhibitory concentration (IC50) values of 33, 35, and 0.5 nM, respectively. VEGFR inhibitors play a pivotal role in blocking tumor angiogenesis.[6] FRUZAQLA^TM works by helping to stop tumors from making new blood vessels and therefore slowing down the growth of cancer.¹

The authorization for the treatment of metastatic colorectal cancer is based on data from two large Phase 3 trials: the multi-regional FRESCO-2 trial, data from which were published in The Lancet, along with the FRESCO trial conducted in China, data from which were published in JAMA. In both trials, FRUZAQLA^TM plus best supportive care demonstrated significant improvements in overall survival, with corresponding improvements in progression free survival, versus placebo plus best supportive care.[7]^,[8]

About Takeda Canada Inc.
Takeda Canada Inc. is the Canadian organization of Takeda Pharmaceutical Company Limited (TSE: 4502/NYSE: TAK), a global, values-based, R&D-driven biopharmaceutical leader headquartered in Japan, committed to discovering and delivering life-transforming treatments, guided by our commitment to patients, our people and the planet. Takeda focuses its R&D efforts on four therapeutic areas: Oncology, Rare Genetics and Hematology, Neuroscience, and Gastroenterology (GI). We also make targeted R&D investments in Plasma-Derived Therapies and Vaccines. We are focusing on developing highly innovative medicines that contribute to making a difference in people's lives by advancing the frontier of new treatment options and leveraging our enhanced collaborative R&D engine and capabilities to create a robust, modality-diverse pipeline. Our employees are committed to improving quality of life for patients and to working with our partners in health care in approximately 80 countries and regions. For more information, visit: https://www.takeda.com/en-ca/ .

[1] FRUZAQLA^TM (fruquintinib capsules), Submission Control 275803, Product Monograph, Takeda Canada Inc. (SEP 10, 2024). Available at: https://takeda.info/en-ca-fruzaqlapm

[2] Canadian Cancer Society. Stages of colorectal cancer. 2025. Available at: https://cancer.ca/en/cancer-information/cancer-types/colorectal/staging#:~:text=For%20stage%202C%2C%20the%20tumour,peritoneum

[3] BC Cancer Foundation. Colorectal Cancer. Available at: https://bccancerfoundation.com/why-give/research/colorectal-cancer/

[4] Atreya CE, Yaeger R, Chu E. Systemic therapy for metastatic colorectal cancer: from current standards to future molecular targeted approaches. Am Soc Clin Oncol Educ Book. 2017;37:246-256. doi:10.1200/EDBK_175679

[5] Vatandoust S, et al. World J Gastroenterol. 2015;21(41):11767-76.

[6] Zhang Y, Zou JY, Wang Z, Wang Y. Fruquintinib: a novel antivascular endothelial growth factor receptor tyrosine kinase inhibitor for the treatment of metastatic colorectal cancer. Cancer Manag Res. 2019 Aug 16;11:7787-7803. doi: 10.2147/CMAR.S215533. PMID: 31496821; PMCID: PMC6701622. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6701622/

[7] Dasari NA, et al. LBA25 – FRESCO-2: A global phase 3 multiregional clinical trial (MRCT) evaluating the efficacy and safety of fruquintinib in patients with refractory metastatic colorectal cancer. Ann Oncol. 2022 Sep;33(suppl_7): S808-S869. Doi:10.1016/annonc/annonc1089.

[8] Li J, Qin S, Xu R, et al. Effect of Fruquintinib vs Placebo on Overall Survival in Patients With Previously Treated Metastatic Colorectal Cancer: The FRESCO Randomized Clinical Trial. JAMA. 2018;319(24):2486–2496. doi:10.1001/jama.2018.7855

SOURCE Takeda Canada Inc.