Carl Zeiss Meditec AG Unsponsored ADR

Showcasing the future of ophthalmic research at ARVO 2025:

• ZEISS Research Data Platform launch - a cloud-based, AI-driven technology solution designed to accelerate discoveries, integrating research and clinical data, and simplifying research workflows.
• ZEISS's collaboration with Boehringer Ingelheim - championing data-driven, personalized care through ZEISS's ongoing research partnership with Boehringer Ingelheim; hear from industry experts during special presentations at the ZEISS booth #1729 and the Boehringer Ingelheim booth #1629. 

JENA, Germany and DUBLIN, Calif., April 30, 2025 /PRNewswire/ -- ZEISS demonstrates a new standard for the future of ophthalmic research at the Association for Research in Vision and Ophthalmology (ARVO) conference, from May 4 – 8, including the introduction of the new ZEISS Research Data Platform (ZEISS RDP), and a spotlight on the ongoing research collaboration with Boehringer Ingelheim to accelerate personalized, data-driven treatment approaches in ophthalmology.

"The future of healthcare is in the data. At ZEISS, we are delivering digital innovation to help shape the future of ophthalmology, investing in research methods that empower clinicians and researchers in balancing their clinical care and research requirements," says Euan S. Thomson, Ph.D., Head of the Digital Business Unit for ZEISS Medical Technology. "The introduction of the ZEISS RDP reflects our commitment to advancing ophthalmic care through smarter, AI-powered tools."

AI technology accelerates discoveries through the ZEISS RDP

At ARVO 2025, ZEISS will introduce the ZEISS RDP, a cloud-based, AI-driven solution designed to transform ophthalmic research workflows. By enabling seamless integration of clinical and research data, ZEISS RDP empowers clinicians and scientists to accelerate discoveries through smarter, more efficient research.

Accelerate research breakthroughs - Using AI-powered tools, clinicians and researchers can swiftly convert their research hypotheses into quantifiable biomarkers. The platform allows users to train their own algorithms and let AI handle complex, time-consuming data analysis, significantly improving efficiency.

Unify research data – Clinicians and researchers can aggregate diverse datasets and formats from multiple sources, facilitating insightful analysis from both medical and surgical imaging data, in addition to other data sources. The platform can consolidate datasets from collaborators while allowing the clinician or research team to retain full control over their data and algorithm with secure user-based access.

Streamline the research workflow – The platform helps clinicians and researchers eliminate silos by integrating research and clinical workflows. Users can automate their data collection from ZEISS FORUM, for example, to reduce manual transfers and errors, increasing overall workflow efficiency.

Following a successful pilot phase, the company plans to launch the ZEISS RDP in select countries throughout 2025.

Ongoing research collaboration with Boehringer Ingelheim

ZEISS Medical Technology and Boehringer Ingelheim continue to advance their research collaboration to champion data-driven artificial intelligence (AI) in the pursuit of earlier detection and prediction capabilities to preserve vision through new treatment pathways and more personalized and precise care for patients with chronic retinal diseases.

"At Boehringer Ingelheim, we're working toward a future in which earlier detection and intervention result in long-term, real-world outcomes that prevent vision loss due to chronic retinal diseases," says Heiko G. Niessen, Ph.D., Global Head of Translational Medicine, Eye Health, at Boehringer Ingelheim. "Our collaboration with ZEISS Medical Technology exemplifies our strategy to work with like-minded partners who share our goal of preserving and protecting eyesight and people's way of life."

ZEISS brings to this collaboration the broad capabilities of its ZEISS Medical Ecosystem – connecting devices and data to enable the development of next-generation analytics, AI technologies, and the potential for new areas of research. Boehringer Ingelheim brings to the collaboration its leading expertise in the discovery and development of breakthrough therapies that transform the lives of people living with underserved medical conditions.

The collaboration between ZEISS and Boehringer Ingelheim will be highlighted during Experts Talks on Wednesday, May 7, at the ZEISS booth #1729 and the Boehringer Ingelheim booth #1629:

• "The Practice of 2030: How Will AI Support You?" presented by Pearse Keane, Professor of Artificial Intelligence at UCL Institute of Ophthalmology & consultant ophthalmologist at Moorfields Eye Hospital, London.
• "How to Tackle Unmet Needs and Treat Diseases Early in the Future?" presented by Sobha Sivaprasad, Professor of Retinal Clinical Research at UCL Institute of Ophthalmology & consultant ophthalmologist at Moorfields Eye Hospital, London.

"Our partnership with Boehringer Ingelheim personifies our strategic focus to drive innovation through collaboration," adds Thomson. "We're harnessing data ecosystems in new ways, enabling partners like Boehringer Ingelheim to make breakthrough discoveries to combat vision problems and improve people's lives."

ZEISS will showcase its latest technology innovations and a series of poster sessions at the ARVO conference from May 4 - 8, 2025, in Salt Lake City, UT, USA, at booth #1729.

For more information, visit www.zeiss.com/med. 

Not all products, services or offers are approved or offered in every market and approved labeling and instructions may vary from one country to another. For country-specific product information, see the appropriate country website. Product specifications are subject to change in design and scope of delivery as a result of ongoing technical development. The statements of the healthcare professionals reflect only their personal opinions and experiences and do not necessarily reflect the opinion of any institution that they are affiliated with. The healthcare professionals alone are responsible for the content of their experience reported and any potential resulting infringements. Carl Zeiss Meditec AG and its affiliates to not have clinical evidence supporting the opinions and statements of the health care professionals nor accept any responsibility or liability of the healthcare professionals' content. The healthcare professionals have a contractual or other financial relationship with Carl Zeiss Meditec AG and its affiliates and have received financial support. 

Contact for investors

Sebastian Frericks

Director Investor Relations

Carl Zeiss Meditec AG

Phone: +49 3641 220 116

Mail: investors.meditec@zeiss.com

Contact for the press

Frank Smith

Head of Global Communications

ZEISS Ophthalmology

Carl Zeiss Meditec Inc.

Phone: +49 3641 220 331

Mail: press.med@zeiss.com

www.zeiss.com/newsroom

Brief Profile

Carl Zeiss Meditec AG (ISIN: DE0005313704), which is listed on the MDAX and TecDAX of the German stock exchange, is one of the world's leading medical technology companies. The Company supplies innovative technologies and application-oriented solutions designed to help doctors improve the quality of life of their patients. The Company offers complete solutions, including implants and consumables, to diagnose and treat eye diseases. The Company creates innovative visualization solutions in the field of microsurgery. With 5,730 employees worldwide, the Group generated revenue of €2,066.1m in fiscal year 2023/24 (to 30 September).

The Group's head office is located in Jena, Germany, and it has subsidiaries in Germany and abroad; more than 50 percent of its employees are based in the USA, Japan, Spain and France. The Center for Application and Research (CARIn) in Bangalore, India and the Carl Zeiss Innovations Center for Research and Development in Shanghai, China, strengthen the Company's presence in these rapidly developing economies. Around 39 percent of Carl Zeiss Meditec AG's shares are in free float. Approx. 59 percent are held by Carl Zeiss AG, one of the world's leading groups in the optical and optoelectronic industries.

For further information visit: www.zeiss.com/med

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Showcasing at ASCRS 2025:

• More than 2 million cases planned with ZEISS VERACITY Surgery Planner: Growing use of one of the leading digital planning solutions for cataract surgery in the U.S. is a testament to the increased adoption of the ZEISS Cataract Workflow digital solutions by surgeons.
• ZEISS MEL 90 broadens refractive treatment portfolio: U.S. availability of both the ZEISS MEL 90 and ZEISS VISUMAX 800 extends the company's LVC market leadership with treatments for myopia, hyperopia, and mixed astigmatism.
• Enhanced cataract portfolio with DORC and FCI: Showcasing cataract solutions from DORC and FCI for the first time in the ZEISS booth #1501.

JENA, Germany and DUBLIN, Calif., April 17, 2025 /PRNewswire/ -- ZEISS Medical Technology will celebrate the rapid adoption of digital cataract solutions and showcase newly available refractive treatment technology at the American Society of Cataract and Refractive Surgery (ASCRS) conference from April 25 – 27 in Los Angeles, CA. ZEISS marks a major milestone in the U.S. with more than 2 million digitally planned cases using the ZEISS VERACITY Surgery Planner,¹ one of the leading digital planning solutions for cataract surgery, which serves as a testament to the growing number of surgeons discovering the benefits of digital workflows in the delivery of patient care and treatments.

"The digital era continues to grow at a rapid pace. Ophthalmologists are increasingly realizing the significant benefits of using digital workflows as the backbone of their medical practices," says Magnus Reibenspiess, Head of Strategic Business Unit Ophthalmology at ZEISS Medical Technology. "ZEISS has much to celebrate at ASCRS this year, including our continued U.S. leadership in digital innovation and ongoing commitment to improving patient care across both the cataract and refractive markets."

Additionally, the ZEISS Refractive Workflow will showcase for the first time both the VISUMAX^® 800 with SMILE^® pro from ZEISS and the MEL^® 90 from ZEISS, helping to further broaden a surgeon's refractive business with improved patient attraction and positive clinical outcomes. Lastly, for the first time, DORC and FCI, both ZEISS companies, are set to present their portfolio of cataract surgical solutions in the ZEISS booth, showcasing the extended benefits of ZEISS's surgical portfolio.

More than 2 million cases planned using ZEISS VERACITY Surgery Planner reflects growing digital adoption by U.S. cataract surgeons

ZEISS VERACITY Surgery Planner is one of the top digital planning solutions for cataract surgery in the U.S. today with thousands of users logging in to plan their surgical cases, pulling data from most modern EMRs, 19 different diagnostic devices, and optional data sources like patient questionnaires, in order to make data-driven informed decisions designed to drive better patient outcomes in clinics and ORs.

At ASCRS, ZEISS will celebrate the significant milestone of its cloud-based ZEISS VERACITY Surgery Planner, with more than 2 million cases planned. A recent study showed that with the ZEISS Cataract Workflow powered by ZEISS VERACITY Surgery Planner, surgeons and staff can save up to 60% of their time per eye compared to traditional paper planning.²

Kerry Solomon, MD, from Carolina Eye Care Physicians, one of the creators of VERACITY prior to its acquisition by ZEISS in 2017, says, "Today we're up to 2 million plans, unbelievable! When we first started developing this solution, I absolutely envisioned we'd get to where we are today, and I'm thrilled with where we're at!"

In addition to proven efficiency gains, new research abstracts presented at this year's ASCRS showcase excellent refractive accuracy and clinical outcomes when adopting the ZEISS Cataract Workflow:

1. Steven C. Schallhorn, MD, ABO, will present a clear benefit of reducing postoperative astigmatism by implanting toric IOLs in patients with lower preoperative corneal astigmatism, leveraging cataract outcomes obtained from VERACITY Surgery Planner's database of 50,850 eyes with preoperative corneal astigmatism between 0.75D and 1.50D.
2. Luke Rebenitsch, MD, ABO, will present a comparison of refractive outcomes in a large cohort of 49,057 eyes undergoing cataract surgery with toric IOL implantation where the use of the ZEISS CALLISTO eye system resulted in significant improvements in terms of post-op refractive outcomes compared to a manual marking approach.
3. Kamran M. Riaz, MD, ABO, will present an analysis of the refractive accuracy of two biometers in a cohort of 222 eyes with prior laser vision correction and implantation of toric multifocal IOLs, highlighting the significantly better performance of total keratometry with the IOLMaster 700.

Enhanced refractive treatment portfolio enables a higher standard of refractive patient care with both the ZEISS VISUMAX 800 and ZEISS MEL 90

ZEISS continues to set high standards in refractive patient care in the U.S. with the availability of both the ZEISS VISUMAX 800 and ZEISS MEL 90. For the first time, the ZEISS MEL 90 will be showcased in the U.S. at ASCRS, extending ZEISS's LVC market leadership with treatment for myopia, hyperopia, and mixed astigmatism.

"The FDA approval of the ZEISS MEL 90 excimer laser is a game changer for refractive surgery in the U.S. I am particularly impressed by the system's ability to simplify treatment planning while delivering highly predictable and tissue-conserving results. This approval marks an exciting chapter for surgeons and patients alike," says Dr. John Doane, Refractive Surgeon, Discover Vision Centers, Kansas City, MO (USA).

The MEL^® 90 from ZEISS aims to offer U.S. surgeons a fast, reliable, and streamlined surgery experience, complementing the VISUMAX^® 800 with SMILE^® pro from ZEISS to help further broaden a surgeon's refractive business with improved patient attraction and positive clinical outcomes.

The ZEISS VISUMAX 800 with ZEISS SMILE pro software enables faster treatment, creating the lenticule in less than 10 seconds thanks to a faster laser pulse repetition rate of 2 MHz.³ The ZEISS femtosecond laser also provides greater flexibility for the surgeon and patient, with a smaller footprint and compatibility with a variety of patient beds, adapting to the clinical environment to provide cutting-edge technology without compromise.

Showcasing the benefits of ZEISS's surgical portfolio to help meet the evolving clinical challenges of surgeons in the U.S.

ZEISS will showcase for the first time together in the ZEISS booth key solutions from DORC and FCI.  This will feature the DORC EVA NEXUS^™ surgical system for cataract and phaco-vitrectomy surgeries. It will also include the DORC VisionBlue^® anterior stain, a trusted choice in more than 10 million cataract surgeries since its introduction. As the only FDA-approved trypan blue stain for anterior applications, it is also authorized for staining Descemet's membrane and trabecular meshwork.  Additionally, the ZEISS booth will feature the FDA-approved Eyejet^® 20C from Morcher^®, built on the gold standard preloaded Eyejet^® system and designed to prevent toric IOLs rotation, providing maximum toric benefits.

ZEISS will showcase its latest offerings and new innovations at the American Society of Cataract and Refractive Surgery (ASCRS) conference from April 25-27, 2025, in Los Angeles, CA, at booth #1501.

For more information, visit www.zeiss.com/med. 

¹ Data on file.

² Gujral, Tarika, and John Hovanesian. "Cataract Surgical Planning Using Online Software vs Traditional Methods." Clinical Ophthalmology (Auckland, N.Z.), U.S. National Library of Medicine, 28 July 2021.

³ Data on file, myopia with optical zone 6.5 mm. 

Not all products, services or offers are approved or offered in every market and approved labeling and instructions may vary from one country to another. For country-specific product information, see the appropriate country website. Product specifications are subject to change in design and scope of delivery as a result of ongoing technical development. The statements of the healthcare professionals reflect only their personal opinions and experiences and do not necessarily reflect the opinion of any institution that they are affiliated with. The healthcare professionals alone are responsible for the content of their experience reported and any potential resulting infringements. Carl Zeiss Meditec AG and its affiliates to not have clinical evidence supporting the opinions and statements of the health care professionals nor accept any responsibility or liability of the healthcare professionals' content. The healthcare professionals have a contractual or other financial relationship with Carl Zeiss Meditec AG and its affiliates and have received financial support. 

Contact for investors

Sebastian Frericks

Director Investor Relations

Carl Zeiss Meditec AG

Phone: +49 3641 220 116

Mail: investors.meditec@zeiss.com

Contact for the press

Frank Smith

Head of Global Communications Ophthalmology

Carl Zeiss Meditec Inc.

Phone: +49 3641 220 331

Mail: press.med@zeiss.com

www.zeiss.com/newsroom          

Brief Profile

Carl Zeiss Meditec AG (ISIN: DE0005313704), which is listed on the MDAX and TecDAX of the German stock exchange, is one of the world's leading medical technology companies. The Company supplies innovative technologies and application-oriented solutions designed to help doctors improve the quality of life of their patients. The Company offers complete solutions, including implants and consumables, to diagnose and treat eye diseases. The Company creates innovative visualization solutions in the field of microsurgery. With 5,730 employees worldwide, the Group generated revenue of €2,066.1m in fiscal year 2023/24 (to 30 September).

The Group's head office is located in Jena, Germany, and it has subsidiaries in Germany and abroad; more than 50 percent of its employees are based in the USA, Japan, Spain and France. The Center for Application and Research (CARIn) in Bangalore, India and the Carl Zeiss Innovations Center for Research and Development in Shanghai, China, strengthen the Company's presence in these rapidly developing economies. Around 39 percent of Carl Zeiss Meditec AG's shares are in free float. Approx. 59 percent are held by Carl Zeiss AG, one of the world's leading groups in the optical and optoelectronic industries.



For further information visit: www.zeiss.com/med

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