77.080002 USD
1.29
1.65%
Last update Dec 17, 3:59 PM EST
Market closed
Day range
77.070000
79.49000
Previous close
78.37000
Open
78.77000
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Ionis Pharmaceuticals, Inc.
77.08
1.29
1.65%

Statistics

Valuation metrics
Market cap
12.48B
Enterprise value
12.51B
Trailing P/E (ttm)
-25.36
Forward P/E
-37.38
PEG ratio
1.61
Price/Sales (ttm)
13.13
Price/Book (mrq)
20.44
Enterprise Value/Revenue
12.94
Enterprise Value/EBITDA
-46.89
Overview
Shares outstanding
161.14M
Float
160.74M
Shares short
15.63M
% Held by insiders
0.62%
% Held by institutions
106.65%
Average volume (10 days)
2.01M
Average volume (90 days)
2.79M
Price summary
52-Week low
23.95
52-Week high
83.61
52-Week change
53.83 224.7%
Beta
0.30
50-Day moving average
75.04
200-Day moving average
49.17
Financials
Fiscal year
Fiscal year ends
Dec 31, 2024
Most recent quarter (mrq)
Sep 30, 2025
Profitability
Profit margin
-26.51%
Operating margin
-102.21%
Operational effectiveness
Return on assets
-5.68%
Return on equity
-40.04%
Income statement
Revenue (ttm)
966.96M
Revenue per share (ttm)
6.09
Quarterly revenue growth (yoy)
17.10%
Gross profit (ttm)
73.71M
EBITDA
-266.80M
Net income to common (ttm)
-256.34M
Diluted EPS (ttm)
-1.61
Quarterly earnings growth (yoy)
Balance sheet
Total cash (mrq)
2.24B
Total cash per share (mrq)
13.85
Total debt (mrq)
2.06B
Total Debt/Equity (mrq)
333.27
Current ratio (mrq)
278.80%
Book value per share (mrq)
3.84
Cash flow
Cash flow statement
-247.01M
Levered free cash flow (LFCF)
-194.03M
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