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0.54990000 USD
0.0199
3.75%
Last update Apr 2, 3:59 PM EDT
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Curis Inc.
0.55
0.02
3.75%

Overview

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Description

Curis Inc. is a biotechnology company focused on discovering and developing drug candidates for treating human cancers. The company's lead program centers on emavusertib (CA-4948), an orally available small molecule inhibitor targeting IRAK4 and FLT3, currently in clinical development for hematologic malignancies including acute myeloid leukemia, myelodysplastic syndromes, and primary central nervous system lymphoma, particularly in patients with relapsed or refractory disease. Emavusertib has received Orphan Drug Designation from the FDA and European Commission, recognizing its potential for treating rare blood cancers. Curis pursues combination therapeutic approaches, pairing emavusertib with established treatments like BTK inhibitors, venetoclax, and azacitidine across multiple indications. The company's pipeline also includes additional candidates such as fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes. Curis advances its programs through clinical collaborations, key opinion leader engagement, and strategic licensing partnerships, including an exclusive license to emavusertib from Aurigene Discovery Technologies Limited. Founded in 2000 and headquartered in Lexington, Massachusetts, Curis operates as an early-stage clinical biotechnology company seeking to address significant unmet needs in oncology.

About

CEO
Mr. James E. Dentzer
Employees
34
Address
Building C
Suite 500 128 Spring Street
Lexington, 02421, MA
United States
Phone
617 503 6500
Website
Instrument type
Common stock
Sector
Healthcare
Industry
Biotechnology
Country
United States
MIC code
XNCM
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Latest press releases

Mar 12, 2026
Curis to Report Fourth Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on March 19, 2026

LEXINGTON, Mass., March 12, 2026 /PRNewswire/ -- Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of emavusertib (CA-4948), an orally available, small molecule IRAK4 and FLT3 inhibitor, today announced that the Company will report its fourth quarter 2025 financial and operating results on Thursday, March 19, 2026, at 4:00 p.m. ET. Management will host a conference call and simultaneous webcast on the same day at 4:30 p.m. ET.

Participants may join by dialing (800)-836-8184 from the United States or (646)-357-8785 from other locations or a live audio webcast can be accessed here or from the investor section of the Curis website. A replay of the conference call will be available at www.curis.com.

About Curis, Inc.

Curis is a biotechnology company focused on the development of emavusertib, an orally available, small molecule IRAK4 and FLT3 inhibitor. Emavusertib is currently being evaluated in the TakeAim Lymphoma Phase 1/2 study (CA-4948-101) of emavusertib in combination with the BTK inhibitor, ibrutinib, in patients with relapsed/refractory primary central nervous system lymphoma (PCNSL) and in the TakeAim CLL Phase 2 study (CA-4948-203) of emavusertib in combination with the BTK inhibitor, zanubrutinib, in chronic lymphocytic leukemia (CLL). The Company has completed its monotherapy and combination studies in acute myeloid leukemia (AML), with additional funding we plan to continue development of emavusertib as a monotherapy and in combination with other agents in AML. Emavusertib has received Orphan Drug Designation from the U.S. Food and Drug Administration for the treatment of PCNSL, AML and MDS and from the European Commission for the treatment of PCNSL. Curis, through its 2015 collaboration with Aurigene Discovery Technologies Limited, has the exclusive license to emavusertib (CA-4948). For more information, visit Curis's website at www.curis.com.

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/curis-to-report-fourth-quarter-2025-financial-and-operating-results-and-host-conference-call-and-webcast-on-march-19-2026-302712824.html

SOURCE Curis, Inc.

Jan 9, 2026
Curis Announces Closing of Private Placement Totaling up to $80.8 Million in Gross Proceeds

Led by Nantahala Capital, Stonepine Capital Management, Pointillist Partners, LLC, and The Red Hook Fund, LP

LEXINGTON, Mass., Jan. 9, 2026 /PRNewswire/ -- Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of emavusertib (CA-4948), an orally available, small molecule IRAK4 and FLT3 inhibitor, today announced the closing of its previously announced private placement (the "PIPE financing") for gross proceeds of up to $80.8 million to the Company, including initial gross proceeds to the Company of approximately $20.2 million, in each case before placement agent fees and offering expenses.

In addition to the healthcare-focused institutional investors listed above, the private placement included participation from other new and existing institutional investors, as well as members of the Company's management team and board of directors.

Laidlaw & Company (UK) Ltd. acted as sole placement agent for the PIPE financing.

About Curis, Inc.

Curis is a biotechnology company focused on the development of emavusertib, an orally available, small molecule IRAK4 and FLT3 inhibitor. Emavusertib is currently being evaluated in the TakeAim Lymphoma Phase 1/2 study (CA-4948-101) of emavusertib in combination with the BTK inhibitor ibrutinib in patients with relapsed/refractory primary central nervous system lymphoma (PCNSL) and in a Phase 2 study (CA-4948-203) of emavusertib in combination with an approved Bruton Tyrosine Kinase Inhibitor in Chronic Lymphocytic Leukemia. The Company has completed its monotherapy and combination studies in acute myeloid leukemia (AML), with additional resources we plan to continue development of emavusertib as a monotherapy and in combination in AML. Emavusertib has received Orphan Drug Designation from the U.S. Food and Drug Administration for the treatment of PCNSL, AML and MDS and from the European Commission for the treatment of PCNSL. Curis, through its 2015 collaboration with Aurigene Discovery Technologies Limited, has the exclusive license to emavusertib (CA-4948).

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/curis-announces-closing-of-private-placement-totaling-up-to-80-8-million-in-gross-proceeds-302657173.html

SOURCE Curis, Inc.

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Market closed

Pre-market opens in 3 days 5 hours 59 minutes
Main market opens in 3 days 11 hours 29 minutes

22:00
00:00
09:30
16:00
23:59

Trading Hours (Monday - Friday):

Pre-market
04:00 - 09:30
Main market
09:30 - 16:00
Post-market
16:00 - 20:00
All times are displayed in the America/New_York timezone (EDT, UTC-04:00).