66.5 EUR
0.88
1.31%
Last update Dec 17, 8:06 AM CET
Main market
Day range
66.5
66.5
Previous close
67.38000
Open
66.5
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Ionis Pharmaceuticals, Inc.
66.50
0.88
1.31%

Statistics

Valuation metrics
Market cap
10.77B
Enterprise value
9.15B
Trailing P/E (ttm)
-21.43
Forward P/E
-37.78
PEG ratio
-37.78
Price/Sales (ttm)
11.14
Price/Book (mrq)
20.38
Enterprise Value/Revenue
11.10
Enterprise Value/EBITDA
-40.22
Overview
Shares outstanding
161.14M
Float
160.74M
Shares short
% Held by insiders
0.62%
% Held by institutions
106.65%
Average volume (10 days)
37
Average volume (90 days)
72
Price summary
52-Week low
22.73
52-Week high
71.62
52-Week change
45.99 202.3%
Beta
0.30
50-Day moving average
64.19
200-Day moving average
42.47
Financials
Fiscal year
Fiscal year ends
Dec 31, 2024
Most recent quarter (mrq)
Sep 30, 2025
Profitability
Profit margin
-26.51%
Operating margin
-102.21%
Operational effectiveness
Return on assets
-5.68%
Return on equity
-40.04%
Income statement
Revenue (ttm)
824.32M
Revenue per share (ttm)
6.09
Quarterly revenue growth (yoy)
17.10%
Gross profit (ttm)
62.84M
EBITDA
-227.44M
Net income to common (ttm)
-218.53M
Diluted EPS (ttm)
-1.37
Quarterly earnings growth (yoy)
Balance sheet
Total cash (mrq)
1.91B
Total cash per share (mrq)
13.85
Total debt (mrq)
1.76B
Total Debt/Equity (mrq)
333.27
Current ratio (mrq)
278.80%
Book value per share (mrq)
3.26
Cash flow
Cash flow statement
-210.58M
Levered free cash flow (LFCF)
-165.41M
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